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Clark International Airport ( IATA: CRK, ICAO: RPLC ), known as Diosdado Macapagal International Airport from 2003 to 2014, is an international airport covering portions of the cities of Angeles and Mabalacat within the Clark Freeport Zone in the province of Pampanga, Philippines. It is located 80 kilometers (50 mi) [6] northwest of Manila.
Adapter molecule crk is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. This protein has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction.
Pennsylvania ( / ˌpɛnsɪlˈveɪniə / ⓘ, lit. 'Penn's forest country' ), officially the Commonwealth of Pennsylvania [b] ( Pennsylvania Dutch: Pennsylvanie ), [7] is a state spanning the Mid-Atlantic, Northeastern, Appalachian, and Great Lakes regions of the United States.
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Current status. Active. PromotionCode.org is a coupon website that provides promotional codes and print coupons to consumers. [3] The corporation's headquarters is in Tallahassee, Florida and it has a west coast office in Las Vegas, Nevada.
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California's capital, Sacramento, is located in the Central Valley . Prior to European colonization, California was one of the most culturally and linguistically diverse areas in pre-Columbian North America. European exploration in the 16th and 17th centuries led to the colonization by the Spanish Empire.