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The Shapiro reaction or tosylhydrazone decomposition is an organic reaction in which a ketone or aldehyde is converted to an alkene through an intermediate hydrazone in the presence of 2 equivalents of organolithium reagent. [1] [2] [3] The reaction was discovered by Robert H. Shapiro in 1967. [4] The Shapiro reaction was used in the Nicolaou ...
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Coupon is located in the northeastern part of Gallitzin Township near the eastern border of Cambria County at the crest of the Allegheny Front, the eastern edge of the Allegheny Plateau. It is located at 40°32′12″N 78°33′54″W (40.5367356, -78.5150162), [1] about 87 miles (140 km) east of Pittsburgh and 9 miles (14 km) west of Altoona.
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Daniel Benjamin " Dan " Shapiro [1] (born August 1, 1969) is an American diplomat who served as United States Ambassador to Israel from 2011 to 2017. He was nominated by President Barack Obama on March 29, 2011, and confirmed by the Senate on May 29. [2] [3] He was sworn in as ambassador by Secretary of State Hillary Clinton on July 8, 2011. [4]
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